Vasomotor Symptoms (VMS)
VMS in menopausal women are commonly known as hot flashes and night sweats. As estrogen levels fall during menopause, the neurons believed to be the key modulators of the heat dissipation response become hyperactive. This leads to VMS, including sensations of heat and/or perspiration that generally last several minutes and are often preceded or followed by sensations of cold and/or shivering.
- Avis, NE, et al. Duration of Menopausal Vasomotor Symptoms Over the Menopause Transition. JAMA Intern Med. 2015 Apr 1; 175(4): 531–539. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4433164/
- Chlebowski RT, Hendrix SL, Langer RD, et al. Influence of estrogen plus progestin on breast cancer and mammography in healthy postmenopausal women: the Women’s Health Initiative Randomized Trial. JAMA 2003; 289:3243.